| Date | Opponent | Location | Time/Result | Record (Conf) | TV/Radio |
|---|---|---|---|---|---|
| August 30, 2008 | Eastern Washington | Lubbock, Texas | W 49-24 | 1-0 (0-0) | - |
| September 6, 2008 | Nevada | Reno, Nevada | W 35-19 | 2-0 (0-0) | Live Internet |
| September 13, 2008 | SMU | Lubbock, Texas | W 43-7 | 3-0 (0-0) | FSN |
| September 20, 2008 | Massachusetts | Lubbock, Texas | W 56-14 | 4-0 (0-0) | - |
| October 4, 2008 | Kansas State | Manhattan, Kansas | W 58-28 | 5-0 (1-0) | ABC |
| October 11, 2008 | Nebraska | Lubbock, Texas | 2:00 PM CT | - | FSN |
| October 18, 2008 | Texas eaTme | College Station, Texas | 11:00 AM CT | - | FSN |
| October 25, 2008 | Kansas | Lawrence, Kansas | TBA | - | - |
| November 1, 2008 | Texas | Lubbock, Texas | TBA | - | - |
| November 8, 2008 | Oklahoma State | Lubbock, Texas | TBA | - | - |
| November 22, 2008 | Oklahoma | Norman, Oklahoma | TBA | - | - |
| November 29, 2008 | Baylor | Lubbock, Texas | TBA | - | - |
| Place Table Description/Information here. | |||||